Transcranial magnetic stimulation, known as TMS, has become a significant advancement in modern psychiatry for patients seeking an evidence-based, noninvasive treatment for depression and related conditions. In a city as diverse and fast-paced as Los Angeles, many individuals experience symptoms that can interfere with daily functioning, decision-making, and overall quality of life. For patients who have not achieved adequate relief with traditional therapies, TMS provides an additional clinical pathway backed by peer reviewed research and supported by national treatment guidelines. Under the guidance of Dr. Thomas Hughes at NeoPsych, patients receive an individualized, thoughtful approach grounded in scientific rigor and patient-centered care.
This article explains the fundamentals of TMS therapy, its clinical applications, what patients can expect during treatment, and how candidacy is determined, helping individuals make informed decisions about their mental health care.
WHAT TMS IS AND HOW IT WORKS
TMS is a noninvasive procedure that uses focused magnetic pulses to stimulate specific regions of the brain associated with mood regulation. These magnetic pulses influence neuronal activity in the dorsolateral prefrontal cortex, an area consistently implicated in major depressive disorder. Multiple controlled studies have demonstrated that repeated stimulation can support improved connectivity and neuroplasticity, contributing to symptom reduction in patients with treatment-resistant depression. A 2024 publication in the Journal of Affective Disorders further confirmed the efficacy of TMS in patients who did not respond to at least two antidepressant medications.
Unlike treatments that affect the entire body, TMS is localized and does not require anesthesia or sedation. Patients remain awake, can drive themselves to and from their appointments, and typically resume normal activities immediately after each session. The treatment process is structured, precise, and guided by advanced technology calibrated to each patient’s motor threshold.
PATIENT CONCERNS, SYMPTOMS, AND INDICATIONS
Patients often seek TMS after experiencing long-standing symptoms of depression that have not improved with medication or psychotherapy alone. These symptoms may include persistent low mood, loss of motivation, reduced concentration, sleep disturbances, and a diminished sense of engagement with daily life. Some patients may feel discouraged after multiple treatment attempts, while others are searching for a solution that does not rely on additional medication or systemic side effects.
Common concerns include whether the treatment is painful, how long results may last, and how TMS interacts with ongoing psychiatric care. Patients may worry about stepping into unfamiliar technology or fear that treatment will be disruptive to their routine. At NeoPsych, Dr. Hughes addresses these concerns through detailed consultation, ensuring patients understand the scientific foundation of TMS and how safety guidelines are maintained throughout every session.
In addition to major depressive disorder, research has expanded to include TMS applications for conditions such as obsessive-compulsive disorder and anxiety symptoms. While FDA clearance remains specific to certain indications, emerging studies continue to explore the broader potential of neuromodulation.
TECHNIQUES, TREATMENT OPTIONS, AND CUSTOMIZED CARE AT NEOPSYCH
NeoPsych provides a refined and carefully structured TMS experience that reflects the practice’s commitment to scientific excellence and individualized care. Treatment begins with a thorough diagnostic evaluation by Dr. Hughes. Patients are guided through a collaborative discussion of their mental health history, previous treatment responses, and current symptoms. This ensures the plan is tailored with precision and attention to each person’s clinical profile.
During the first TMS session, Dr. Hughes determines the patient’s motor threshold, which serves as the baseline for customizing stimulation intensity. Each subsequent session builds on this foundation. A standard treatment course typically involves five sessions per week for approximately six weeks. NeoPsych uses FDA-cleared TMS technology designed for accuracy, comfort, and consistent therapeutic dosing.
Every patient’s experience is monitored closely. Adjustments to positioning, frequency, or stimulation parameters can be made when clinically appropriate. NeoPsych’s approach prioritizes safety, patient comfort, and measurable outcomes, supported by Dr. Hughes’ background in both psychiatry and neuroscience.
RECOVERY, EXPECTED OUTCOMES, AND TREATMENT EXPERIENCE
Because TMS is noninvasive, there is no recovery period in the traditional sense. Patients typically remain seated comfortably throughout the session, which lasts approximately 20 minutes depending on the protocol. Afterward, they return to work, school, or daily responsibilities with minimal interruption.
The most commonly reported sensation during TMS is a tapping feeling on the scalp, which often becomes more tolerable as treatment continues. Mild headache or temporary scalp tenderness may occur but usually resolves quickly. These effects are well documented in the scientific literature and are considered manageable for most patients.
Regarding outcomes, improvement is gradual and builds over several weeks. Studies show that many patients receiving TMS experience meaningful reductions in depressive symptoms, and some achieve full remission. A recent 2023 randomized controlled trial published in Brain Stimulation reported that patients who responded to TMS maintained symptom improvement for several months with appropriate follow-up care.
Dr. Hughes emphasizes realistic expectations. TMS is not an immediate or universal solution, but for many individuals, it provides a clinically significant opportunity for improved mood, restored cognitive function, and a renewed ability to engage in daily life. At NeoPsych, monitoring tools and follow-up visits help support continuity of progress after completing the active treatment phase.
WHO IS A CANDIDATE FOR TMS
An ideal candidate for TMS is an adult diagnosed with major depressive disorder who has not achieved adequate relief from traditional treatments, including antidepressant medications or psychotherapy. Patients who cannot tolerate medication side effects may also be suitable candidates.
Candidacy is established through a thorough evaluation that assesses psychiatric history, treatment timeline, and medical contraindications. TMS is generally appropriate for patients without seizure disorders, implanted metallic devices near the head, or unstable medical conditions. Pregnant patients may be considered on a case-by-case basis depending on clinical needs and existing research guidance.
Individuals who value a structured, noninvasive treatment option that allows them to remain engaged in daily activities often find TMS well aligned with their preferences.
INVITATION TO BEGIN CARE
Choosing to pursue treatment for depression is a meaningful step toward improved well-being. For individuals in Los Angeles seeking an evidence-based approach guided by a psychiatrist with extensive clinical and academic experience, NeoPsych provides a thoughtful, patient-centered environment. To learn more about TMS therapy or to schedule a consultation with Dr. Thomas Hughes, visit or contact us.